The first two deaths attributed to the cyclosporiasis outbreak have been reported in Michigan, the state's health department announced Monday. Both individuals had significant underlying health conditions that may have been exacerbated by the parasitic infection and subsequent dehydration, according to the Michigan Department of Health and Human Services (MDHHS). The department stated that no further details would be released.

These fatalities occur as the number of confirmed cyclosporiasis cases in Michigan has surpassed 11,000, reaching a total of 11,234, which includes 193 hospitalizations, according to MDHHS data. Cyclosporiasis is generally not considered life-threatening in the United States, and fatalities are uncommon.

Federal health officials have connected cases in Michigan and eight other states to shredded iceberg lettuce served at certain Taco Bell locations. Taylor Farms, the supplier of the implicated lettuce, has initiated a voluntary recall of all iceberg lettuce originating from central Mexico. Consumers have been advised to discard or return any such lettuce products.

Taco Bell confirmed last month that it has discontinued the use of lettuce from Taylor Farms de Mexico across all its restaurants. The Centers for Disease Control and Prevention (CDC) acknowledged the two cyclosporiasis-related deaths in Michigan among individuals with pre-existing health conditions as part of the ongoing outbreak.

Nationally, the CDC is investigating other cyclosporiasis outbreaks and illnesses that are not associated with this particular multi-state event. Since May 1, over 18,000 cyclosporiasis cases have been reported across 45 states, as per CDC data updated on Wednesday. This includes at least 6,707 laboratory-confirmed cases and 423 hospitalizations.

The CDC also indicated awareness of an additional 11,500 cases that are pending laboratory confirmation or further investigation. The agency notes that it can take up to six weeks to confirm if a reported illness is part of its official tally, meaning national figures may lag behind state-reported totals.

Internationally, the UK Health Security Agency (UKHSA) recently reported a significant increase in cyclosporiasis infections among travelers returning from Mexico. Between April 30 and July 15, 67 cases were recorded in England, Wales, and Scotland, a notable rise compared to the annual average of 93 cases between 2022 and 2025. The UKHSA is advising travelers to take preventative measures, such as maintaining good food and water hygiene abroad.

The source of the outbreak is believed to be the parasite Cyclospora cayetanensis, a microscopic organism that can cause gastrointestinal illness. The investigation into the precise source and the full extent of the outbreak is ongoing, with health authorities continuing to monitor the situation and provide guidance to the public.